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quinupristin/dalfopristin will raise the level or influence of bosentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.quinupristin/dalfopristin will increase the level or effect of bazedoxifene/conjugated estrogens by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.quinup